Resolution of P-Sterogenic 1-Phenylphosphin-2-en-4-one 1-Oxide into Two Enantiomers by (R,R)-TADDOL and Conformational Diversity of the Phosphinenone Ring and TADDOL in the Crystal State

The resolution of racemic 1-phenylphosphin-2-en-4-one 1-oxide (2), was achieved through the fractional crystallization of its diastereomeric complexes with (4R,5R)-(−)-2,2-dimethyl -α,α,α′,α′-tetraphenyl-dioxolan-4,5-dimethanol (R,R-TADDOL) followed by the liberation of the individual enantiomers of...

Descripción completa

Detalles Bibliográficos
Autores principales: Łastawiecka, Elżbieta, Włodarczyk, Adam, Kozioł, Anna E., Małuszyńska, Hanna, Pietrusiewicz, K. Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621017/
https://www.ncbi.nlm.nih.gov/pubmed/34833965
http://dx.doi.org/10.3390/molecules26226873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621017/
https://www.ncbi.nlm.nih.gov/pubmed/34833965
http://dx.doi.org/10.3390/molecules26226873

Ejemplares similares