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Natural Flt3Lg-Based Chimeric Antigen Receptor (Flt3-CAR) T Cells Successfully Target Flt3 on AML Cell Lines

Relapsed/refractory acute myeloid leukemia (AML) cannot be cured with chemotherapy alone, as the blasts survive the treatment. Chimeric antigen receptor (CAR) approaches for AML are being actively developed. CARs promote immune reactions through recognition of the target molecular epitopes at the su...

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Detalles Bibliográficos
Autores principales: Maiorova, Varvara, Mollaev, Murad D., Vikhreva, Polina, Kulakovskaya, Elena, Pershin, Dmitry, Chudakov, Dmitriy M., Kibardin, Alexey, Maschan, Michael A., Larin, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621097/
https://www.ncbi.nlm.nih.gov/pubmed/34835169
http://dx.doi.org/10.3390/vaccines9111238