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Multiscale Modeling of Amyloid Fibrils Formed by Aggregating Peptides Derived from the Amyloidogenic Fragment of the A-Chain of Insulin

Computational prediction of molecular structures of amyloid fibrils remains an exceedingly challenging task. In this work, we propose a multi-scale modeling procedure for the structure prediction of amyloid fibrils formed by the association of ACC(1-13) aggregation-prone peptides derived from the N-...

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Detalles Bibliográficos
Autores principales: Koliński, Michał, Dec, Robert, Dzwolak, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621111/
https://www.ncbi.nlm.nih.gov/pubmed/34830214
http://dx.doi.org/10.3390/ijms222212325