Investigation of Thiocarbamates as Potential Inhibitors of the SARS-CoV-2 Mpro

In the present study we tested, using the microscale thermophoresis technique, a small library of thionocarbamates, thiolocarbamates, sulfide and disulfide as potential lead compounds for SARS-CoV-2 Mpro drug design. The successfully identified binder is a representative of the thionocarbamates grou...

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Detalles Bibliográficos
Autores principales: Papaj, Katarzyna, Spychalska, Patrycja, Hopko, Katarzyna, Kapica, Patryk, Fisher, Andre, Lill, Markus A., Bagrowska, Weronika, Nowak, Jakub, Szleper, Katarzyna, Smieško, Martin, Kasprzycka, Anna, Góra, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621115/
https://www.ncbi.nlm.nih.gov/pubmed/34832935
http://dx.doi.org/10.3390/ph14111153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621115/
https://www.ncbi.nlm.nih.gov/pubmed/34832935
http://dx.doi.org/10.3390/ph14111153

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