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Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin

Mitomycin has a unique chemical structure and contains densely assembled functionalities with extraordinary antitumor activity. The previously proposed mitomycin C biosynthetic pathway has caused great attention to decipher the enzymatic mechanisms for assembling the pharmaceutically unprecedented c...

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Detalles Bibliográficos
Autores principales: Leng, Dongjin, Sheng, Yong, Wang, Hengyu, Wei, Jianhua, Ou, Yixin, Deng, Zixin, Bai, Linquan, Kang, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621148/
https://www.ncbi.nlm.nih.gov/pubmed/34833880
http://dx.doi.org/10.3390/molecules26226791