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Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin
Mitomycin has a unique chemical structure and contains densely assembled functionalities with extraordinary antitumor activity. The previously proposed mitomycin C biosynthetic pathway has caused great attention to decipher the enzymatic mechanisms for assembling the pharmaceutically unprecedented c...
Autores principales: | Leng, Dongjin, Sheng, Yong, Wang, Hengyu, Wei, Jianhua, Ou, Yixin, Deng, Zixin, Bai, Linquan, Kang, Qianjin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621148/ https://www.ncbi.nlm.nih.gov/pubmed/34833880 http://dx.doi.org/10.3390/molecules26226791 |
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