Manipulating Estrogenic/Anti-Estrogenic Activity of Triphenylethylenes towards Development of Novel Anti-Neoplastic SERMs

Selective estrogen receptor modulators (SERMs) act as estrogen receptor (ERα) agonists or antagonists depending on the target issue. Tamoxifen (TAM) (a non-steroidal triphenylethylene derivative) was the first SERM approved as anti-estrogen for the treatment of metastatic breast cancer. On the hunt...

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Detalles Bibliográficos
Autores principales: Elnakib, Heba E., Ramsis, Marian M., Albably, Nouran O., Vector, Merna A., Weigand, Jan J., Schwedtmann, Kai, Wober, Jannette, Zierau, Oliver, Vollmer, Günter, Abadi, Ashraf H., Ahmed, Nermin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621172/
https://www.ncbi.nlm.nih.gov/pubmed/34830456
http://dx.doi.org/10.3390/ijms222212575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621172/
https://www.ncbi.nlm.nih.gov/pubmed/34830456
http://dx.doi.org/10.3390/ijms222212575

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