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Manipulating Estrogenic/Anti-Estrogenic Activity of Triphenylethylenes towards Development of Novel Anti-Neoplastic SERMs

Selective estrogen receptor modulators (SERMs) act as estrogen receptor (ERα) agonists or antagonists depending on the target issue. Tamoxifen (TAM) (a non-steroidal triphenylethylene derivative) was the first SERM approved as anti-estrogen for the treatment of metastatic breast cancer. On the hunt...

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Detalles Bibliográficos
Autores principales:	Elnakib, Heba E., Ramsis, Marian M., Albably, Nouran O., Vector, Merna A., Weigand, Jan J., Schwedtmann, Kai, Wober, Jannette, Zierau, Oliver, Vollmer, Günter, Abadi, Ashraf H., Ahmed, Nermin S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621172/ https://www.ncbi.nlm.nih.gov/pubmed/34830456 http://dx.doi.org/10.3390/ijms222212575

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