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Sensitivity and Specificity of CD19.CAR-T Cell Detection by Flow Cytometry and PCR

Chimeric-antigen-receptor-T (CAR-T) cells are currently revolutionizing the field of cancer immunotherapy. Therefore, there is an urgent need for CAR-T cell monitoring by clinicians to assess cell expansion and persistence in patients. CAR-T cell manufacturers and researchers need to evaluate transd...

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Detalles Bibliográficos
Autores principales: Schanda, Nicola, Sauer, Tim, Kunz, Alexander, Hückelhoven-Krauss, Angela, Neuber, Brigitte, Wang, Lei, Hinkelbein, Mandy, Sedloev, David, He, Bailin, Schubert, Maria-Luisa, Müller-Tidow, Carsten, Schmitt, Michael, Schmitt, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621201/
https://www.ncbi.nlm.nih.gov/pubmed/34831430
http://dx.doi.org/10.3390/cells10113208