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An Oligomannuronic Acid-Sialic Acid Conjugate Capable of Inhibiting Aβ42 Aggregation and Alleviating the Inflammatory Response of BV-2 Microglia

Oligomannuronic acid (MOS) from seaweed has antioxidant and anti-inflammatory activities. In this study, MOS was activated at the terminal to obtain three different graft complexes modified with sialic acid moiety (MOS-Sia). The results show that MOS-Sia addition can reduce the β-structure formation...

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Detalles Bibliográficos
Autores principales: Wu, Jianrong, Wu, Miaosen, Zhang, Hongtao, Zhan, Xiaobei, Wu, Nian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621211/
https://www.ncbi.nlm.nih.gov/pubmed/34830217
http://dx.doi.org/10.3390/ijms222212338