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An Oligomannuronic Acid-Sialic Acid Conjugate Capable of Inhibiting Aβ42 Aggregation and Alleviating the Inflammatory Response of BV-2 Microglia
Oligomannuronic acid (MOS) from seaweed has antioxidant and anti-inflammatory activities. In this study, MOS was activated at the terminal to obtain three different graft complexes modified with sialic acid moiety (MOS-Sia). The results show that MOS-Sia addition can reduce the β-structure formation...
Autores principales: | Wu, Jianrong, Wu, Miaosen, Zhang, Hongtao, Zhan, Xiaobei, Wu, Nian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621211/ https://www.ncbi.nlm.nih.gov/pubmed/34830217 http://dx.doi.org/10.3390/ijms222212338 |
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