Matrix Metalloproteinases Inhibition by Doxycycline Rescues Extracellular Matrix Organization and Partly Reverts Myofibroblast Differentiation in Hypermobile Ehlers-Danlos Syndrome Dermal Fibroblasts: A Potential Therapeutic Target?

Hypermobile Ehlers-Danlos syndrome (hEDS) is the most frequent type of EDS and is characterized by generalized joint hypermobility and musculoskeletal manifestations which are associated with chronic pain, and mild skin involvement along with the presence of more than a few comorbid conditions. Desp...

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Detalles Bibliográficos
Autores principales: Chiarelli, Nicola, Zoppi, Nicoletta, Venturini, Marina, Capitanio, Daniele, Gelfi, Cecilia, Ritelli, Marco, Colombi, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621259/
https://www.ncbi.nlm.nih.gov/pubmed/34831458
http://dx.doi.org/10.3390/cells10113236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621259/
https://www.ncbi.nlm.nih.gov/pubmed/34831458
http://dx.doi.org/10.3390/cells10113236

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