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DYRK1A Overexpression in Mice Downregulates the Gonadotropic Axis and Disturbs Early Stages of Spermatogenesis

Down syndrome (DS) is the most common chromosomal disorder. It is responsible for intellectual disability (ID) and several medical conditions. Although men with DS are thought to be infertile, some spontaneous paternities have been reported. The few studies of the mechanism of infertility in men wit...

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Detalles Bibliográficos
Autores principales: Dard, Rodolphe, Moreau, Manon, Parizot, Estelle, Ghieh, Farah, Brehier, Leslie, Kassis, Nadim, Serazin, Valérie, Lamaziere, Antonin, Racine, Chrystèle, di Clemente, Nathalie, Vialard, François, Janel, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621272/
https://www.ncbi.nlm.nih.gov/pubmed/34828406
http://dx.doi.org/10.3390/genes12111800