Artemisinin Binds and Inhibits the Activity of Plasmodium falciparum Ddi1, a Retroviral Aspartyl Protease

Reduced sensitivity of the human malaria parasite, Plasmodium falciparum, to Artemisinin and its derivatives (ARTs) threatens the global efforts towards eliminating malaria. ARTs have been shown to cause ubiquitous cellular and genetic insults, which results in the activation of the unfolded protein...

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Detalles Bibliográficos
Autores principales: Onchieku, Noah Machuki, Kumari, Sonam, Pandey, Rajan, Sharma, Vaibhav, Kumar, Mohit, Deshmukh, Arunaditya, Kaur, Inderjeet, Mohmmed, Asif, Gupta, Dinesh, Kiboi, Daniel, Gaur, Naseem, Malhotra, Pawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621276/
https://www.ncbi.nlm.nih.gov/pubmed/34832620
http://dx.doi.org/10.3390/pathogens10111465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621276/
https://www.ncbi.nlm.nih.gov/pubmed/34832620
http://dx.doi.org/10.3390/pathogens10111465

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