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Artemisinin Binds and Inhibits the Activity of Plasmodium falciparum Ddi1, a Retroviral Aspartyl Protease
Reduced sensitivity of the human malaria parasite, Plasmodium falciparum, to Artemisinin and its derivatives (ARTs) threatens the global efforts towards eliminating malaria. ARTs have been shown to cause ubiquitous cellular and genetic insults, which results in the activation of the unfolded protein...
Autores principales: | Onchieku, Noah Machuki, Kumari, Sonam, Pandey, Rajan, Sharma, Vaibhav, Kumar, Mohit, Deshmukh, Arunaditya, Kaur, Inderjeet, Mohmmed, Asif, Gupta, Dinesh, Kiboi, Daniel, Gaur, Naseem, Malhotra, Pawan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621276/ https://www.ncbi.nlm.nih.gov/pubmed/34832620 http://dx.doi.org/10.3390/pathogens10111465 |
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