BiP Heterozigosity Aggravates Pathological Deterioration in Experimental Amyotrophic Lateral Sclerosis

In the present study, we investigated the involvement of the chaperone protein BiP (also known as GRP78 or Hspa5), a master regulator of intracellular proteostasis, in two mouse models of neurodegenerative diseases: amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). To this end, we us...

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Detalles Bibliográficos
Autores principales: Gómez-Almería, Marta, Burgaz, Sonia, Costas-Insua, Carlos, Rodríguez-Cueto, Carmen, Santos-García, Irene, Rodríguez-Crespo, Ignacio, García, Concepción, Guzmán, Manuel, de Lago, Eva, Fernández-Ruiz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621319/
https://www.ncbi.nlm.nih.gov/pubmed/34830414
http://dx.doi.org/10.3390/ijms222212533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621319/
https://www.ncbi.nlm.nih.gov/pubmed/34830414
http://dx.doi.org/10.3390/ijms222212533

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