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BiP Heterozigosity Aggravates Pathological Deterioration in Experimental Amyotrophic Lateral Sclerosis

In the present study, we investigated the involvement of the chaperone protein BiP (also known as GRP78 or Hspa5), a master regulator of intracellular proteostasis, in two mouse models of neurodegenerative diseases: amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). To this end, we us...

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Detalles Bibliográficos
Autores principales:	Gómez-Almería, Marta, Burgaz, Sonia, Costas-Insua, Carlos, Rodríguez-Cueto, Carmen, Santos-García, Irene, Rodríguez-Crespo, Ignacio, García, Concepción, Guzmán, Manuel, de Lago, Eva, Fernández-Ruiz, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621319/ https://www.ncbi.nlm.nih.gov/pubmed/34830414 http://dx.doi.org/10.3390/ijms222212533

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