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A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor

OBJECTIVE: Natural sources of molecular diversity remain of utmost importance as a reservoir of proteins and peptides with unique biological functions. We recently identified such a family of viral insulin-like peptides (VILPs). We sought to advance the chemical methods in synthesis to explore the s...

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Detalles Bibliográficos
Autores principales: Zhang, Fa, Altindis, Emrah, Kahn, C. Ronald, DiMarchi, Richard D., Gelfanov, Vasily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621328/
https://www.ncbi.nlm.nih.gov/pubmed/34400347
http://dx.doi.org/10.1016/j.molmet.2021.101316