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A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor
OBJECTIVE: Natural sources of molecular diversity remain of utmost importance as a reservoir of proteins and peptides with unique biological functions. We recently identified such a family of viral insulin-like peptides (VILPs). We sought to advance the chemical methods in synthesis to explore the s...
Autores principales: | Zhang, Fa, Altindis, Emrah, Kahn, C. Ronald, DiMarchi, Richard D., Gelfanov, Vasily |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621328/ https://www.ncbi.nlm.nih.gov/pubmed/34400347 http://dx.doi.org/10.1016/j.molmet.2021.101316 |
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