Ammonium Formate-Pd/C as a New Reducing System for 1,2,4-Oxadiazoles. Synthesis of Guanidine Derivatives and Reductive Rearrangement to Quinazolin-4-Ones with Potential Anti-Diabetic Activity

1,2,4-Oxadiazole is a heterocycle with wide reactivity and many useful applications. The reactive O-N bond is usually reduced using molecular hydrogen to obtain amidine derivatives. NH(4)CO(2)H-Pd/C is here demonstrated as a new system for the O-N reduction, allowing us to obtain differently substit...

Descripción completa

Detalles Bibliográficos
Autores principales: Marzullo, Paola, Vasto, Sonya, Buscemi, Silvestre, Pace, Andrea, Nuzzo, Domenico, Palumbo Piccionello, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621334/
https://www.ncbi.nlm.nih.gov/pubmed/34830187
http://dx.doi.org/10.3390/ijms222212301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621334/
https://www.ncbi.nlm.nih.gov/pubmed/34830187
http://dx.doi.org/10.3390/ijms222212301

Ejemplares similares