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Ammonium Formate-Pd/C as a New Reducing System for 1,2,4-Oxadiazoles. Synthesis of Guanidine Derivatives and Reductive Rearrangement to Quinazolin-4-Ones with Potential Anti-Diabetic Activity

1,2,4-Oxadiazole is a heterocycle with wide reactivity and many useful applications. The reactive O-N bond is usually reduced using molecular hydrogen to obtain amidine derivatives. NH(4)CO(2)H-Pd/C is here demonstrated as a new system for the O-N reduction, allowing us to obtain differently substit...

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Detalles Bibliográficos
Autores principales:	Marzullo, Paola, Vasto, Sonya, Buscemi, Silvestre, Pace, Andrea, Nuzzo, Domenico, Palumbo Piccionello, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621334/ https://www.ncbi.nlm.nih.gov/pubmed/34830187 http://dx.doi.org/10.3390/ijms222212301

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