Therapeutic Benefit of Galectin-1: Beyond Membrane Repair, a Multifaceted Approach to LGMD2B

Two of the main pathologies characterizing dysferlinopathies are disrupted muscle membrane repair and chronic inflammation, which lead to symptoms of muscle weakness and wasting. Here, we used recombinant human Galectin-1 (rHsGal-1) as a therapeutic for LGMD2B mouse and human models. Various redox a...

Descripción completa

Detalles Bibliográficos
Autores principales: Vallecillo-Zúniga, Mary L., Poulson, Peter Daniel, Luddington, Jacob S., Arnold, Christian J., Rathgeber, Matthew, Kartchner, Braden C., Hayes, Spencer, Gill, Hailie, Valdoz, Jonard C., Spallino, Jonathan L., Garfield, Seth, Dodson, Ethan L., Arthur, Connie M., Stowell, Sean R., Van Ry, Pam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621416/
https://www.ncbi.nlm.nih.gov/pubmed/34831431
http://dx.doi.org/10.3390/cells10113210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621416/
https://www.ncbi.nlm.nih.gov/pubmed/34831431
http://dx.doi.org/10.3390/cells10113210

Ejemplares similares