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Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells

The insulin receptor isoform A (IR-A) plays an increasingly recognized role in fetal growth and tumor biology in response to circulating insulin and/or locally produced IGF2. This role seems not to be shared by the IR isoform B (IR-B). We aimed to dissect the specific impact of IR isoforms in modula...

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Detalles Bibliográficos
Autores principales: Vella, Veronica, Giuliano, Marika, La Ferlita, Alessandro, Pellegrino, Michele, Gaudenzi, Germano, Alaimo, Salvatore, Massimino, Michele, Pulvirenti, Alfredo, Dicitore, Alessandra, Vigneri, Paolo, Vitale, Giovanni, Malaguarnera, Roberta, Morrione, Andrea, Sims, Andrew H., Ferro, Alfredo, Maggiolini, Marcello, Lappano, Rosamaria, De Francesco, Ernestina Marianna, Belfiore, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621444/
https://www.ncbi.nlm.nih.gov/pubmed/34831367
http://dx.doi.org/10.3390/cells10113145