New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design

Twenty lupane type A-ring azepano-triterpenoids were synthesized from betulin and its related derivatives and their antitubercular activity against Mycobacterium tuberculosis, mono-resistant MTB strains, and nontuberculous strains Mycobacterium abscessus and Mycobacterium avium were investigated in...

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Detalles Bibliográficos
Autores principales: Kazakova, Oxana, Racoviceanu, Roxana, Petrova, Anastasiya, Mioc, Marius, Militaru, Adrian, Udrescu, Lucreția, Udrescu, Mihai, Voicu, Adrian, Cummings, Jason, Robertson, Gregory, Ordway, Diane J., Slayden, Richard A., Șoica, Codruța
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621456/
https://www.ncbi.nlm.nih.gov/pubmed/34830423
http://dx.doi.org/10.3390/ijms222212542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621456/
https://www.ncbi.nlm.nih.gov/pubmed/34830423
http://dx.doi.org/10.3390/ijms222212542

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