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Gene-Activated Matrix with Self-Assembly Anionic Nano-Device Containing Plasmid DNAs for Rat Cranial Bone Augmentation

We have developed nanoballs, a biocompatible self-assembly nano-vector based on electrostatic interactions that arrange anionic macromolecules to polymeric nanomaterials to create nucleic acid carriers. Nanoballs exhibit low cytotoxicity and high transfection efficiently in vivo. This study investig...

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Detalles Bibliográficos
Autores principales: Hara, Masahito, Sumita, Yoshinori, Kodama, Yukinobu, Iwatake, Mayumi, Yamamoto, Hideyuki, Shido, Rena, Narahara, Shun, Ogaeri, Takunori, Sasaki, Hitoshi, Asahina, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621468/
https://www.ncbi.nlm.nih.gov/pubmed/34832496
http://dx.doi.org/10.3390/ma14227097