Tumor-Derived Small Extracellular Vesicles Induce Pro-Inflammatory Cytokine Expression and PD-L1 Regulation in M0 Macrophages via IL-6/STAT3 and TLR4 Signaling Pathways

Tumor-associated macrophages play a key role in promoting tumor progression by exerting an immunosuppressive phenotype associated with the expression of programmed cell death ligand 1 (PD-L1). It is well known that tumor-derived small extracellular vesicles (SEVs) affect the tumor microenvironment,...

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Detalles Bibliográficos
Autores principales: Pucci, Marzia, Raimondo, Stefania, Urzì, Ornella, Moschetti, Marta, Di Bella, Maria Antonietta, Conigliaro, Alice, Caccamo, Nadia, La Manna, Marco Pio, Fontana, Simona, Alessandro, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621495/
https://www.ncbi.nlm.nih.gov/pubmed/34829995
http://dx.doi.org/10.3390/ijms222212118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621495/
https://www.ncbi.nlm.nih.gov/pubmed/34829995
http://dx.doi.org/10.3390/ijms222212118

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