Butyrate and Class I Histone Deacetylase Inhibitors Promote Differentiation of Neonatal Porcine Islet Cells into Beta Cells

Neonatal porcine islets-like clusters (NPICCs) are a promising source for cell therapy of type 1 diabetes. Freshly isolated NPICCs are composed of progenitor cells and endocrine cells, which undergo a maturation process lasting several weeks until the normal beta cell function has developed. Here, w...

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Detalles Bibliográficos
Autores principales: Zhang, Yichen, Lei, Yutian, Honarpisheh, Mohsen, Kemter, Elisabeth, Wolf, Eckhard, Seissler, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621544/
https://www.ncbi.nlm.nih.gov/pubmed/34831471
http://dx.doi.org/10.3390/cells10113249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621544/
https://www.ncbi.nlm.nih.gov/pubmed/34831471
http://dx.doi.org/10.3390/cells10113249

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