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Cabozantinib Is Effective in Melanoma Brain Metastasis Cell Lines and Affects Key Signaling Pathways

Melanomas have a high potential to metastasize to the brain. Recent advances in targeted therapies and immunotherapies have changed the therapeutical landscape of extracranial melanomas. However, few patients with melanoma brain metastasis (MBM) respond effectively to these treatments and new therap...

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Detalles Bibliográficos
Autores principales: Mannsåker, Trond Are, Hoang, Tuyen, Aasen, Synnøve Nymark, Bjørnstad, Ole Vidhammer, Parajuli, Himalaya, Sundstrøm, Terje, Thorsen, Frits Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621572/
https://www.ncbi.nlm.nih.gov/pubmed/34830178
http://dx.doi.org/10.3390/ijms222212296