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Targeting Oxidative Stress, NLRP3 Inflammasome, and Autophagy by Fraxetin to Combat Doxorubicin-Induced Cardiotoxicity

Doxorubicin belongs to the class of anthracycline antibiotics that is widely used in the treatment protocols of a wide range of malignancies. The major deleterious effect of doxorubicin use is the possible occurrence of cardiotoxicity. This study aimed to delineate the possible effects of targeting...

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Detalles Bibliográficos
Autores principales: Kabel, Ahmed M., Salama, Samir A., Adwas, Almokhtar A., Estfanous, Remon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621693/
https://www.ncbi.nlm.nih.gov/pubmed/34832970
http://dx.doi.org/10.3390/ph14111188