Mokko Lactone Attenuates Doxorubicin-Induced Hepatotoxicity in Rats: Emphasis on Sirt-1/FOXO1/NF-κB Axis

Doxorubicin (DOX), a common chemotherapeutic agent, suffers serious adverse effects including hepatotoxicity. Mokko lactone (ML) is a guainolide sesquiterpene with promising biological activities. The study aimed to evaluate the protection offered by ML against hepatotoxicity induced by DOX in rats....

Descripción completa

Detalles Bibliográficos
Autores principales: Sirwi, Alaa, Shaik, Rasheed A., Alamoudi, Abdulmohsin J., Eid, Basma G., Kammoun, Ahmed K., Ibrahim, Sabrin R. M., Mohamed, Gamal A., Abdallah, Hossam M., Abdel-Naim, Ashraf B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621765/
https://www.ncbi.nlm.nih.gov/pubmed/34836397
http://dx.doi.org/10.3390/nu13114142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621765/
https://www.ncbi.nlm.nih.gov/pubmed/34836397
http://dx.doi.org/10.3390/nu13114142

Ejemplares similares