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Mokko Lactone Attenuates Doxorubicin-Induced Hepatotoxicity in Rats: Emphasis on Sirt-1/FOXO1/NF-κB Axis

Doxorubicin (DOX), a common chemotherapeutic agent, suffers serious adverse effects including hepatotoxicity. Mokko lactone (ML) is a guainolide sesquiterpene with promising biological activities. The study aimed to evaluate the protection offered by ML against hepatotoxicity induced by DOX in rats....

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Detalles Bibliográficos
Autores principales:	Sirwi, Alaa, Shaik, Rasheed A., Alamoudi, Abdulmohsin J., Eid, Basma G., Kammoun, Ahmed K., Ibrahim, Sabrin R. M., Mohamed, Gamal A., Abdallah, Hossam M., Abdel-Naim, Ashraf B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621765/ https://www.ncbi.nlm.nih.gov/pubmed/34836397 http://dx.doi.org/10.3390/nu13114142

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