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New Compounds with Bioisosteric Replacement of Classic Choline Kinase Inhibitors Show Potent Antiplasmodial Activity

In the fight against Malaria, new strategies need to be developed to avoid resistance of the parasite to pharmaceutics and other prevention barriers. Recently, a Host Directed Therapy approach based on the suppression of the starting materials uptake from the host by the parasite has provided excell...

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Detalles Bibliográficos
Autores principales: Aguilar-Troyano, Francisco José, Torretta, Archimede, Rubbini, Gianluca, Fasiolo, Alberto, Luque-Navarro, Pilar María, Carrasco-Jimenez, María Paz, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, González-Pacanowska, Dolores, Parisini, Emilio, Lopez-Cara, Luisa Carlota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621770/
https://www.ncbi.nlm.nih.gov/pubmed/34834257
http://dx.doi.org/10.3390/pharmaceutics13111842