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IL-10 mRNA Engineered MSCs Demonstrate Enhanced Anti-Inflammation in an Acute GvHD Model

Mesenchymal stem cells (MSCs) are used in various studies to induce immunomodulatory effects in clinical conditions associated with immune dysregulation such as graft versus host disease (GvHD). However, most of these clinical trials failed to go beyond early phase 2 studies because of limited effic...

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Detalles Bibliográficos
Autores principales: Zhang, Cuiping, Delawary, Mina, Huang, Peng, Korchak, Jennifer A., Suda, Koji, Zubair, Abba C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621791/
https://www.ncbi.nlm.nih.gov/pubmed/34831324
http://dx.doi.org/10.3390/cells10113101