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Antibacterial Activity of T22, a Specific Peptidic Ligand of the Tumoral Marker CXCR4

CXCR4 is a cytokine receptor used by HIV during cell attachment and infection. Overexpressed in the cancer stem cells of more than 20 human neoplasias, CXCR4 is a convenient antitumoral drug target. T22 is a polyphemusin-derived peptide and an effective CXCR4 ligand. Its highly selective CXCR4 bindi...

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Detalles Bibliográficos
Autores principales: Serna, Naroa, Carratalá, José Vicente, Conchillo-Solé, Oscar, Martínez-Torró, Carlos, Unzueta, Ugutz, Mangues, Ramón, Ferrer-Miralles, Neus, Daura, Xavier, Vázquez, Esther, Villaverde, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621837/
https://www.ncbi.nlm.nih.gov/pubmed/34834337
http://dx.doi.org/10.3390/pharmaceutics13111922