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Antiproliferative activity of CD44 siRNA-PEI-PEG nanoparticles in glioblastoma: involvement of AKT signaling

BACKGROUND AND PURPOSE: Glioblastoma multiforme (GBM) is the most invasive type of cancer which starts inside the brain. GBM cells were found to have similar properties to glioblastoma cancer stem cells. CD44 can be used as a marker of the cancer stem cells in a subset of glioblastoma tumor cells. R...

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Detalles Bibliográficos
Autores principales: Mahinfar, Parvaneh, Mokhtarzadeh, Ahad, Baradaran, Behzad, Siasi Torbati, Elham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621842/
https://www.ncbi.nlm.nih.gov/pubmed/34909046
http://dx.doi.org/10.4103/1735-5362.329928