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Oxypeucedanin and isoimperatorin extracted from Prangos ferulacea (L.) Lindl protect PC12 pheochromocytoma cells from oxidative stress and apoptosis induced by doxorubicin

BACKGROUND AND PURPOSE: Doxorubicin (DOX) as a chemotherapeutic agent has been widely used in the treatment of various types of cancer. However, DOX exerts a toxic effect on normal tissues such as the brain. Furanocoumarins reduce the risk of cardiovascular and brain diseases because of their antiox...

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Detalles Bibliográficos
Autores principales: Jalilian, Fereshteh, Moieni-Arya, Maryam, Hosseinzadeh, Leila, Shokoohinia, Yalda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621846/
https://www.ncbi.nlm.nih.gov/pubmed/34909040
http://dx.doi.org/10.4103/1735-5362.329922