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Some novel hybrid quinazoline-based heterocycles as potent cytotoxic agents

BACKGROUND AND PURPOSE: In this study, some new cytotoxic hybrid structures were synthesized by combining pyrazolinone and imidazolinone rings with quinazoline pharmacophores. EXPERIMENTAL APPROACH: The benzoxazinone, pyrazolo-quinazoline fused ring, and imidazolinone anchored quinazoline derivative...

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Detalles Bibliográficos
Autores principales: Malekzadeh, Mahla, Dadkhah, Shadi, Khodarahmi, Ghadam Ali, Asadi, Parvin, Hassanzadeh, Farshid, Rostami, Mahboubeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621847/
https://www.ncbi.nlm.nih.gov/pubmed/34909041
http://dx.doi.org/10.4103/1735-5362.329923