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The Progestin Medroxyprogesterone Acetate Affects HIV-1 Production in Human Lymphoid Tissue Explants in a Dose-Dependent and Glucocorticoid-like Fashion

The association between the use of the injectable contraceptive depot medroxyprogesterone acetate and HIV-1 susceptibility has been addressed mainly in respect to the changes occurring in the female genital mucosa and blood. However, one of the main sites of HIV-1 pathogenesis is lymphoid organs. To...

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Detalles Bibliográficos
Autores principales: Vanpouille, Christophe, Günaydın, Gökçe, Jangard, Mattias, Clerici, Mario, Margolis, Leonid, Broliden, Kristina, Introini, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621851/
https://www.ncbi.nlm.nih.gov/pubmed/34835109
http://dx.doi.org/10.3390/v13112303