Mild Copper-Catalyzed, l-Proline-Promoted Cross-Coupling of Methyl 3-Amino-1-benzothiophene-2-carboxylate

Cu-catalyzed N-arylation is a useful tool for the chemical modification of aromatic heterocycles. Herein, an efficient carbon–nitrogen cross-coupling of methyl 3-amino-1-benzothiophene-2-carboxylate with a range of (hetero)aryl iodides using CuI, l-proline and Cs(2)CO(3) in dioxane at moderate tempe...

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Detalles Bibliográficos
Autores principales: Kederienė, Vilija, Jaglinskaitė, Indrė, Voznikaitė, Paulina, Rousseau, Jolanta, Rollin, Patrick, Šačkus, Algirdas, Tatibouët, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621900/
https://www.ncbi.nlm.nih.gov/pubmed/34833915
http://dx.doi.org/10.3390/molecules26226822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621900/
https://www.ncbi.nlm.nih.gov/pubmed/34833915
http://dx.doi.org/10.3390/molecules26226822

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