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Spray-Dried Paracetamol/Polyvinylpyrrolidone Amorphous Solid Dispersions: Part I—Stability of Powders and Tablets

The formulation of active pharmaceutical ingredients (APIs) in amorphous solid dispersions (ASDs) is a promising approach to improve the bioavailability of poorly soluble compounds. However, problems often arise in the production of tablets from ASDs regarding the compressibility and recrystallizati...

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Detalles Bibliográficos
Autores principales: Ritters, Lena, Tian, Yuanyuan, Reichl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621994/
https://www.ncbi.nlm.nih.gov/pubmed/34834353
http://dx.doi.org/10.3390/pharmaceutics13111938