A Comprehensive Review of HLA and Severe Cutaneous Adverse Drug Reactions: Implication for Clinical Pharmacogenomics and Precision Medicine

Human leukocyte antigen (HLA) encoded by the HLA gene is an important modulator for immune responses and drug hypersensitivity reactions as well. Genetic polymorphisms of HLA vary widely at population level and are responsible for developing severe cutaneous adverse drug reactions (SCARs) such as St...

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Detalles Bibliográficos
Autores principales: Kloypan, Chiraphat, Koomdee, Napatrupron, Satapornpong, Patompong, Tempark, Therdpong, Biswas, Mohitosh, Sukasem, Chonlaphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622011/
https://www.ncbi.nlm.nih.gov/pubmed/34832859
http://dx.doi.org/10.3390/ph14111077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622011/
https://www.ncbi.nlm.nih.gov/pubmed/34832859
http://dx.doi.org/10.3390/ph14111077

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