Bcl-xL Reduces Chinese Giant Salamander Iridovirus-Induced Mitochondrial Apoptosis by Interacting with Bak and Inhibiting the p53 Pathway

Chinese giant salamander iridovirus (GSIV) infection could lead to mitochondrial apoptosis in this animal, a process that involves B-cell lymphoma-2 (BCL-2) superfamily molecules. The mRNA expression level of Bcl-xL, a crucial antiapoptotic molecule in the BCL-2 family, was reduced in early infectio...

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Detalles Bibliográficos
Autores principales: Li, Yiqun, Fan, Yuding, Zhou, Yong, Jiang, Nan, Xue, Mingyang, Meng, Yan, Liu, Wenzhi, Zhang, Jingjing, Lin, Ge, Zeng, Lingbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622046/
https://www.ncbi.nlm.nih.gov/pubmed/34835028
http://dx.doi.org/10.3390/v13112224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622046/
https://www.ncbi.nlm.nih.gov/pubmed/34835028
http://dx.doi.org/10.3390/v13112224

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