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Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins

Hemorrhage induced by snake venom metalloproteinases (SVMPs) is a complex phenomenon that involves capillary disruption and blood extravasation. HF3 (hemorrhagic factor 3) is an extremely hemorrhagic SVMP of Bothrops jararaca venom. Studies using proteomic approaches revealed targets of HF3 among in...

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Detalles Bibliográficos
Autores principales: Bertholim, Luciana, Chaves, Alison F. A., Oliveira, Ana K., Menezes, Milene C., Asega, Amanda F., Tashima, Alexandre K., Zelanis, Andre, Serrano, Solange M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622078/
https://www.ncbi.nlm.nih.gov/pubmed/34822548
http://dx.doi.org/10.3390/toxins13110764