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Cathepsin C Regulates Cytokine-Induced Apoptosis in β-Cell Model Systems

Emerging evidence suggests that several of the lysosomal cathepsin proteases are genetically associated with type 1 diabetes (T1D) and participate in immune-mediated destruction of the pancreatic β cells. We previously reported that the T1D candidate gene cathepsin H is downregulated by pro-inflamma...

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Detalles Bibliográficos
Autores principales: Fløyel, Tina, Frørup, Caroline, Størling, Joachim, Pociot, Flemming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622156/
https://www.ncbi.nlm.nih.gov/pubmed/34828301
http://dx.doi.org/10.3390/genes12111694