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Electrostatic Forces Mediate the Specificity of RHO GTPase-GDI Interactions

Three decades of research have documented the spatiotemporal dynamics of RHO family GTPase membrane extraction regulated by guanine nucleotide dissociation inhibitors (GDIs), but the interplay of the kinetic mechanism and structural specificity of these interactions is as yet unresolved. To address...

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Detalles Bibliográficos
Autores principales: Mosaddeghzadeh, Niloufar, Kazemein Jasemi, Neda S., Majolée, Jisca, Zhang, Si-Cai, Hordijk, Peter L., Dvorsky, Radovan, Ahmadian, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622166/
https://www.ncbi.nlm.nih.gov/pubmed/34830380
http://dx.doi.org/10.3390/ijms222212493