Cargando…
Fate of Tableted Freeze-Dried siRNA Lipoplexes in Gastrointestinal Environment
The incorporation of siRNA into nanocarriers is mandatory to facilitate its intracellular delivery, as siRNA itself cannot enter cells. However, the incorporation of these nanocarriers into oral, solid dosage forms and their fate in the gastrointestinal environment is yet to be explored. In the pres...
Autores principales: | Rehman, Asad Ur, Busignies, Virginie, Coelho Silva Ribeiro, Marcela, Almeida Lage, Nayara, Tchoreloff, Pierre, Escriou, Virginie, Charrueau, Christine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622262/ https://www.ncbi.nlm.nih.gov/pubmed/34834222 http://dx.doi.org/10.3390/pharmaceutics13111807 |
Ejemplares similares
-
Neuroprotective Effect of siRNA Entrapped in Hyaluronic Acid-Coated Lipoplexes by Intravitreal Administration
por: Ribeiro, Marcela Coelho Silva, et al.
Publicado: (2021) -
Effect of pre-freezing and saccharide types in freeze-drying of siRNA lipoplexes on gene-silencing effects in the cells by reverse transfection
por: Tang, Min, et al.
Publicado: (2020) -
Mechanistic Approach to Stability Studies as a Tool for the Optimization and Development of New Products Based on L. rhamnosus Lcr35® in Compliance with Current Regulations
por: Muller, Claudia, et al.
Publicado: (2013) -
Coupling of importin beta binding peptide on plasmid DNA: transfection efficiency is increased by modification of lipoplex's physico-chemical properties
por: Carrière, Marie, et al.
Publicado: (2003) -
Development of siRNA lipoplexes for intracellular delivery in lung cancer cells
por: Khatri, N., et al.
Publicado: (2012)