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Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn’s Disease

Secretory immunoglobulin A (sIgA) plays an important role in gut barrier protection by shaping the resident microbiota community, restricting the growth of bacterial pathogens, and enhancing host protective immunity via immunological exclusion. Here, we found that a portion of microbiota-driven sIgA...

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Detalles Bibliográficos
Autores principales: Doron, Itai, Mesko, Marissa, Li, Xin V., Kusakabe, Takato, Leonardi, Irina, Shaw, Dustin G., Fiers, William D., Lin, Woan-Yu, Bialt-DeCelie, Meghan, Román, Elvira, Longman, Randy S., Pla, Jesus, Wilson, Patrick C., Iliev, Iliyan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622360/
https://www.ncbi.nlm.nih.gov/pubmed/34811531
http://dx.doi.org/10.1038/s41564-021-00983-z