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Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn’s Disease
Secretory immunoglobulin A (sIgA) plays an important role in gut barrier protection by shaping the resident microbiota community, restricting the growth of bacterial pathogens, and enhancing host protective immunity via immunological exclusion. Here, we found that a portion of microbiota-driven sIgA...
Autores principales: | Doron, Itai, Mesko, Marissa, Li, Xin V., Kusakabe, Takato, Leonardi, Irina, Shaw, Dustin G., Fiers, William D., Lin, Woan-Yu, Bialt-DeCelie, Meghan, Román, Elvira, Longman, Randy S., Pla, Jesus, Wilson, Patrick C., Iliev, Iliyan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622360/ https://www.ncbi.nlm.nih.gov/pubmed/34811531 http://dx.doi.org/10.1038/s41564-021-00983-z |
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