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Analysis of the Physicochemical Properties, Replication and Pathophysiology of a Massively Glycosylated Hepatitis B Virus HBsAg Escape Mutant

Mutations in HBsAg, the surface antigen of the hepatitis B virus (HBV), might affect the serum HBV DNA level of HBV-infected patients, since the reverse transcriptase (RT) domain of HBV polymerase overlaps with the HBsAg-coding region. We previously identified a diagnostic escape mutant (W3S) HBV th...

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Detalles Bibliográficos
Autores principales: Hossain, Md. Golzar, Suwanmanee, Yadarat, Du, Kaili, Ueda, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622389/
https://www.ncbi.nlm.nih.gov/pubmed/34835134
http://dx.doi.org/10.3390/v13112328