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MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs

Chronic liver disease mediated by the activation of hepatic stellate cells (HSCs) leads to liver fibrosis. The signal adaptor MyD88 of Toll-like receptor (TLR) signaling is involved during the progression of liver fibrosis. However, the specific role of MyD88 in myeloid cells in liver fibrosis has n...

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Detalles Bibliográficos
Autores principales: Ge, Shuang, Yang, Wei, Chen, Haiqiang, Yuan, Qi, Liu, Shi, Zhao, Yongxiang, Zhang, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622429/
https://www.ncbi.nlm.nih.gov/pubmed/34830293
http://dx.doi.org/10.3390/ijms222212413